Fat Loss & Body Composition
This chapter provides an educational overview of compounds commonly researched for their potential role in appetite regulation, metabolic health, energy expenditure and body composition.
Information is intended for educational purposes and summarizes current areas of scientific research.
Retatrutide
Overview
Triple receptor agonist (GLP-1/GIP/Glucagon) under clinical investigation for obesity and metabolic health.
How It Works
Activates GLP-1, GIP and glucagon receptors involved in appetite and energy balance.
Potential Areas of Research
- Appetite regulation
- Body composition support
- Metabolic health
- Energy expenditure
- Blood glucose regulation
- Lean mass preservation during weight management
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.
Tirzepatide
Overview
Dual GLP-1/GIP receptor agonist widely studied in obesity and type 2 diabetes.
How It Works
Activates GLP-1 and GIP receptors to influence appetite and glucose metabolism.
Potential Areas of Research
- Appetite regulation
- Satiety
- Body composition
- Metabolic health
- Blood glucose regulation
- Insulin sensitivity
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.
Semaglutide
Overview
GLP-1 receptor agonist extensively studied for weight management and metabolic health.
How It Works
Activates GLP-1 receptors involved in appetite and gastric emptying.
Potential Areas of Research
- Reduced appetite
- Increased satiety
- Weight management
- Glucose control
- Cardiometabolic health
Educational Note
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.
Cagrilintide
Overview
Amylin analogue researched for appetite regulation and body composition.
How It Works
Mimics amylin, a hormone involved in satiety.
Potential Areas of Research
- Increased satiety
- Reduced hunger
- Body composition support
- Potential complementary use with GLP-1 therapies
Educational Note
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.
Tesamorelin
Overview
Synthetic GHRH analogue approved for a specific indication involving excess visceral fat in HIV-associated lipodystrophy and researched for body composition.
How It Works
Stimulates endogenous growth hormone release.
Potential Areas of Research
- Visceral fat research
- Body composition
- Growth hormone release
- IGF-1 support
- Lean body mass research
Educational Note
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.
5-Amino-1MQ
Overview
Research compound studied as an NNMT inhibitor.How It Works
Inhibits NNMT, an enzyme involved in cellular metabolism.Potential Areas of Research
- Metabolic health research
- Energy metabolism
- Body composition
- Insulin sensitivity research
MOTS-c
Overview
Mitochondrial-derived peptide investigated for metabolic flexibility and energy production.How It Works
Influences mitochondrial signalling and cellular energy use.Potential Areas of Research
- Energy metabolism
- Insulin sensitivity
- Exercise metabolism
- Healthy ageing research
- Mitochondrial function
SLU-PP-332
Overview
Investigational research compound studied as an exercise mimetic.
How It Works
Activates estrogen-related receptor pathways linked to energy metabolism.
Potential Areas of Research
- Energy expenditure
- Fat oxidation research
- Endurance research
- Mitochondrial activity
Educational Note
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.
NAD+
Overview
Essential coenzyme involved in cellular energy production.
How It Works
Supports redox reactions critical for ATP production.
Potential Areas of Research
- Cellular energy
- Mitochondrial support
- Healthy ageing research
- Metabolic function
Educational Note
This section summarizes current scientific research and is provided for educational purposes only. It is not medical advice.